Britta Qualmann Lab

Thereby membrane trafficking processes play an essential role.

Britta community wardrobe. Salvarezza sylvie deborde ryan schreiner fabien campagne michael m. Human proteins containing this domain. Qualmann and kelly 2000 and by the fact that a surplus of dynamin binding syndapin sh3 domains inhibits receptor mediated endocytosis in both permeabilized cell assays simpson et al 1999 and intact cells qualmann and kelly 2000.

The relevance of the interaction with dynamin is strongly supported by coimmunoprecipitation studies of the endogenous proteins qualmann et al 1999. Extensive structural work on bar domains has revealed a common curved. Synaptic contacts of neurons represent specialized cell cell contact and communication interfaces.

The sorting nexin family of proteins includes several members that possess a bar domain including the well characterized snx1 and snx9. Please submit your application by email to michaelkesselsatmedunijenade pdfs preferred. Kessels britta qualmann alfredo caceres geri kreitzer and enrique rodriguez boulan mol biol cell.

Nonnenplan 24 d07743 jena germany. The role of cytoskeletal and cytomatrix components in the structural and functional organization of neurons nerve cell communication requires specialy subcellular compartments and structures which need to be organized on the molecular level. Britta qualmann pd dr.

The project examines the molecular basis of abp1 functions in the formation and the plasticity of synaptic cell cell contacts haeckel et al. Lim kinase and cofilin regulate actin filament population required for dynamin dependent apical carrier fission for tgn. The institute provides a stimulating research environment with excellent technical equipment in a recently completely reconstructed building right in the center of jena one of the top ranking and most lively biotech cities of germany.

Single cells like their higher units of organization man and animals are in constant contact with their environment to exchange matter and information. Friedrich schiller university jena. Among such membrane shapers the superfamily of binamphiphysinrvs bar domain proteins has recently taken center stage.

A plethora of cell biological processes involve modulations of cellular membranes. Institute for biochemistry i university hospital jenafriedrich schiller university jena nonnenplan 24 jena thueringen d07743 germany. Work of the lab of britta qualmann also demonstrated that syndapin i is crucial for proper targeting of the large gtpase dynamin to membranes.

1 institute for biochemistry i university hospital jenafriedrich schiller university jena jena germany corresponding authors. Britta qualmann researchgate the professional network for scientists. Michael manfred kessels 1.